<h3>Title</h3>
<h3>Curvature remodelling of cell membranes: from the biochemistry to the <span style="font-size: 12.16px;">biophysics</span></h3>
<p><strong><span style="font-size: 12.16px;"><span style="text-decoration: underline;">Abstract</span> :</span></strong></p>
<p style="text-align: justify;">A biological cell is a complex soft matter system in which many of physical and chemical <span style="font-size: 12.16px;">processes span multiple spatial and temporal scales. The various theoretical and </span><span style="font-size: 12.16px;">computational tools developed in the context of soft matter physics can be utilized to build </span><span style="font-size: 12.16px;">highly quantitative models to investigate these processes, and gain new insights </span><span style="font-size: 12.16px;">specifically in the mesoscale (order of 100 nm). In this talk, I will show how computational </span><span style="font-size: 12.16px;">models at various spatiotemporal scales along with multiscale bridging techniques may </span><span style="font-size: 12.16px;">be used to develop biophysical models that closely relate to the underlying biochemical </span><span style="font-size: 12.16px;">information. I will demonstrate these aspects using two specific problems: (i) estimating </span><span style="font-size: 12.16px;">the excess area in a cell membrane through the extraction of tethers, and (ii) atomistic to </span><span style="font-size: 12.16px;">thermodynamic descriptions of the spontaneous membrane remodeling activity of ENTH </span><span style="font-size: 12.16px;">and Exo70 domain containing proteins.</span></p>